Volume 16, Issue 4 (2-2011)                   Intern Med Today 2011, 16(4): 0-0 | Back to browse issues page

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Monavar S H R I, Shamsi Shahrabadi M, Vahabpour R, Azizi M. The Effects of the Anti-viral (Nepeta Pungens) on Measles Virus in Laboratory Environment. Intern Med Today 2011; 16 (4)
URL: http://imtj.gmu.ac.ir/article-1-1031-en.html
1- Tehran University of Medical Sciences , hrmonavari@yahoo.com
2- Tehran University of Medical Sciences
Abstract:   (9101 Views)
Abstract Background and Aim: The chemical anti-viral drugs used nowadays have some main problems such as low number and type, low therapeutic index, limited clinical use and high toxicity. So, it seems essential to investigate and evaluate new pharmaceutical compounds for achieving new treatment methods. The main goal of this research is to study the effect of juice of Nepeta pungens on the measles virus replication cycle. Materials and Methods: This study was an experimental one in which initially the toxicity of Nepeta pungens on vero cells was investigated. Then, its anti-viral effects in the concentration range less than toxicity were evaluated through Tissue Culture Infection Dose 50 (TCLD50) method. Results: The results showed that the juice of mint has a controlling effect on the measles virus replication. The results, also, indicated that the most effect of anti-viral the juice of Nepeta pungens was observed in the early stages of the virus replication cycle. Conclusion: The juice of Nepeta pungens can be the suitable choice for further research to achieve new anti-viral factors.
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Type of Study: Original | Subject: Basic Medical Science
Received: 2011/02/19 | Published: 2011/02/15

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