Volume 31, Issue 3 (Summer 2025)
Intern Med Today 2025, 31(3): 0-0 |
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Mardaneh J, Abbasi S, Mohammadzadeh A, Delghandi F, Dastani M. Scientific Mapping of Research on Hodgkin Lymphoma (HL) Associated with Epstein–Barr Virus (EBV) in the Web of Science (1983–2025). , Intern Med Today. 2025; 31 (3)
URL: http://imtj.gmu.ac.ir/article-1-4180-en.html
URL: http://imtj.gmu.ac.ir/article-1-4180-en.html
1- Department of Microbiology, Faculty of Medicine, Infectious Diseases Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.
2- Infectious Diseases Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.
3- Department of Knowledge and Information Science, Payam-e-Noor University, Tehran, Iran.
4- Infectious Diseases Research Center, Gonabad University of Medical Sciences, Gonabad, Iran. ,meisam.dastani@gmail.com
2- Infectious Diseases Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.
3- Department of Knowledge and Information Science, Payam-e-Noor University, Tehran, Iran.
4- Infectious Diseases Research Center, Gonabad University of Medical Sciences, Gonabad, Iran. ,
Abstract: (27 Views)
Aims: Epstein-Barr virus (EBV), as one of the oncogenic viruses of the Herpesviridae family, is associated with a spectrum of lymphoid malignancies, including Hodgkin lymphoma (HL). Despite numerous studies in this field, the present study was conducted to perform a scientometric analysis and visualize the scientific map of indexed research outputs on Hodgkin lymphoma associated with EBV in the Web of Science database.
Materials and Methods: This scientometric study extracted data from the Web of Science database using a search strategy based on Medical Subject Headings (MeSH), combining terms related to Hodgkin lymphoma and EBV infection. A total of 1,160 scientific documents published between 1983 and August 25, 2025, were included through a census approach after the inclusion and exclusion criteria had been applied. The exclusion criterion was publication in a language other than English. Data were analyzed using VOSviewer software, including co-authorship analyses at the author and country levels and a keyword co-occurrence analysis.
Results: The publication trend of scientific outputs comprised three distinct phases: a period of limited output (1983–1990), substantial growth (1991–2003), peaking at 50 articles in 2003, and a period of relative stabilization (2004–2025). Niedobitek, G. was identified as the most productive author. The United States was the leading country, with 333 documents and 17,126 citations, followed by Japan and Germany. Keyword co-occurrence analysis identified “Epstein–Barr virus” as the most central concept in the network. The research themes were interpreted within four broad areas: pathogenesis and immunodeficiency, lymphoproliferative disorders, molecular diagnosis, and clinical outcomes and treatment. The overlay visualization indicated a shift in research focus from diagnostic methods toward prognosis, immunotherapy, and clinical management.
Conclusion: This field has evolved from an emerging topic into an established research domain with extensive international networks. The findings emphasize the necessity of strengthening international and interdisciplinary collaborations, developing integrated research utilizing molecular and clinical data, and paying greater attention to prognostic factors and treatment response.
Materials and Methods: This scientometric study extracted data from the Web of Science database using a search strategy based on Medical Subject Headings (MeSH), combining terms related to Hodgkin lymphoma and EBV infection. A total of 1,160 scientific documents published between 1983 and August 25, 2025, were included through a census approach after the inclusion and exclusion criteria had been applied. The exclusion criterion was publication in a language other than English. Data were analyzed using VOSviewer software, including co-authorship analyses at the author and country levels and a keyword co-occurrence analysis.
Results: The publication trend of scientific outputs comprised three distinct phases: a period of limited output (1983–1990), substantial growth (1991–2003), peaking at 50 articles in 2003, and a period of relative stabilization (2004–2025). Niedobitek, G. was identified as the most productive author. The United States was the leading country, with 333 documents and 17,126 citations, followed by Japan and Germany. Keyword co-occurrence analysis identified “Epstein–Barr virus” as the most central concept in the network. The research themes were interpreted within four broad areas: pathogenesis and immunodeficiency, lymphoproliferative disorders, molecular diagnosis, and clinical outcomes and treatment. The overlay visualization indicated a shift in research focus from diagnostic methods toward prognosis, immunotherapy, and clinical management.
Conclusion: This field has evolved from an emerging topic into an established research domain with extensive international networks. The findings emphasize the necessity of strengthening international and interdisciplinary collaborations, developing integrated research utilizing molecular and clinical data, and paying greater attention to prognostic factors and treatment response.
Keywords: Collaboration network, Epstein-Barr virus (EBV), Hodgkin Lymphoma (HL), Keyword Co-occurrence Analysis, Scientometrics, Scientific Map
Type of Study: Original |
Subject:
Diseases
Received: 2024/01/21 | Accepted: 2025/03/1 | Published: 2025/05/30
Received: 2024/01/21 | Accepted: 2025/03/1 | Published: 2025/05/30
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