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Volume 12, Issue 1 (vol-1 2006)                   Intern Med Today 2006, 12(1): 42-47 | Back to browse issues page

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Ghaderi R, Mohammadi Fard M. Comparison of the efficacy of emollient with heliotherapy for the relief pruritus in patients undergoing hemodialysis. Intern Med Today 2006; 12 (1) :42-47
URL: http://imtj.gmu.ac.ir/article-1-45-en.html
1- , rezaghaderi@yahoo.com
Abstract:   (8985 Views)
Abstract Background and Aim: Pruritus is the most important skin symptom in uremic patients. A large number of treatments for it have been used such as, topical emollients reduce the elevated serum calcium , phosphorus and PTH concentration, administration of antihistamines, oral charcoal, ketotifen, Erythropoietin (EPO) and ultraviolet ray. The aim of this study was to compare the efficacy of emollient with heliotherapy for the relief pruritus in patients undergoing hemodialysis. Materials and Methods: In this clinical trial, 25 adult patients suffering from CRF with Pruritus and were on maintenance hemodialysis at least for 2 months, (and the cause of their itching was not internal or skin disorders), were studied. The patients were divided in 3 groups according to Hattori system (A, B and C). The intensity of pruritus was graded from 0 to 4. The patients had not any contraindication for heliotherapy. At first, patients used emollient therapy for 8 weeks. Then the patients were treated with heliotherapy for 8 week (after 2 months without treatment).Hemoglobin, serum calcium and phosphorus concentration were measured (before and after the treatments). Then the intensity of pruritus was compared before and after the treatments. Then the data were analyzed using SPSS package, Wilcoxen and McNemar tests. Results: There were not significant differences between serum calcium and phosphorus concentration, pruritus intensity, before and after emollienttherapy but there were significant differences between all of them before and after heliotherapy (P<0.001, P<0.003, P<0.005 respectively). There were not significant differences between Hemoglobin concentration before and after treatment by emollient or heliotherapy. Conclusion: Heliotherapy is an effective and safe treatment for the relief pruritus in patients undergoing hemodialysis.
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Type of Study: Original | Subject: Internal Medicine
Received: 2007/07/2 | Published: 2006/04/15

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