Tahere Blouchi, Mojtaba Kianmehr, Jahanshir Tavakolizade, Mahdi Basiri-Moghadam, Fateme Biabani,
Volume 21, Issue 2 (Summer 2015)
Abstract
Abstract Aims: Dialysis patients have experienced some degree of pain, especially foot pain. Some complementary interventions such as muscle relaxation are effective in relieving pain. This study was performed with the aim of assessing the effect of muscle relaxation on hemodialysis patients’ pain. Materials & Methods: This randomized controlled clinical trial was conducted on 90 hemodialysis patients of Khatamolanbia and Imam Ali hemodialysis centers of Zahedan during 2013 and 2014. The patients were chosen by purposive sampling based on inclusion criteria and randomly divided into control and experimental groups. Pain intensity was measured by McGill questionnaire before intervention. Then, Benson muscle relaxation was taught to patients’ of case group and was performed by them for 15-20 minutes twice a day for a month. The control group received no training. The pain intensity of two groups was compared after one month. The data were analyzed using Chi-square, independent T and Mann-Whitney tests by SPSS 21 software. Findings: Most of the patients were men, married, housekeeper with under diploma education and the mean age of them was 43.0±15.0 years. There was a significant decrease in pain intensity in the intervention group compared to the control (p=0.03). Conclusion: The muscle relaxation technique can be employed to reduce pain in hemodialysis patients.
Zahra Delavarian, Seyyed Issac Hashemi, Leyla Vazifeh Mostaan, Sina Mozaffari Jovin, Alireza Biabani, Ala Ghazi,
Volume 28, Issue 1 (Winter 2021)
Abstract
Aims: Oral Squamous Cell Carcinoma (OSCC) is the most frequent malignancy of oral cavity. Early diagnosis of OSCC can provide early treatment and increase the survival rate. Recently, the level of salivary biomarkers has been studied for the early diagnosis of different cancers. This study aims to assess the Zinc Finger protein 510 (ZNF510) concentration, a novel biomarker for the diagnosis of OSCC in early stages, in salvia of patients with OSCC and healthy individuals as
Methods & Materials: In this study conducted in 2019, 21 OSCC patients and 21 healthy individuals participated and their unstimulated saliva were collected by the spitting method. The ZNF510 concentration was determined using the ELISA technique. All statitical analyses were performed in SPSS software, version 23. The significance level was set at 0.05 for all tests.
Findings: The mean of ZNF510 protein was significantly higher in OSCC patients than in healthy subjects (P=0.019), but after considering age as a confounder variable, the difference was not significant (P=0.090). Moreover, in patients with OSCC, the mean of ZNF510 in those with grade II lesion was significantly higher than in those with lesion grade I (P=0.001).
Conclusion: Age has an effect on the ZNF510 concentration in saliva. Therefore, further studies by consideration of age factor and using larger sample sizes are recommended.
