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Abstract Background and Aim: The chemical anti-viral drugs used nowadays have some main problems such as low number and type, low therapeutic index, limited clinical use and high toxicity. So, it seems essential to investigate and evaluate new pharmaceutical compounds for achieving new treatment methods. The main goal of this research is to study the effect of juice of Nepeta pungens on the measles virus replication cycle. Materials and Methods: This study was an experimental one in which initially the toxicity of Nepeta pungens on vero cells was investigated. Then, its anti-viral effects in the concentration range less than toxicity were evaluated through Tissue Culture Infection Dose 50 (TCLD50) method. Results: The results showed that the juice of mint has a controlling effect on the measles virus replication. The results, also, indicated that the most effect of anti-viral the juice of Nepeta pungens was observed in the early stages of the virus replication cycle. Conclusion: The juice of Nepeta pungens can be the suitable choice for further research to achieve new anti-viral factors.

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Aims: Severe exercises lead to higher blood homocysteine levels, as well as heat shock protein 72 (HSP72). The aim of the study was to compare homocysteine and HSP72 responses following moderate-intensity continuous and high-intensity interval exercises in the sedentary women.

Materials & Methods: In the semi-experimental study, 20 sedentary and healthy young female students were studied in Islamic Azad University, Sari Branch, in 2014. The subjects, selected via purposeful and available sampling method, were randomly divided into two groups including continuous exercise and high-intensity interval exercise (n=10 persons per group). 40-minute running on the treadmill with 60-65% of maximum consumed oxygen was conducted in continuous group. In addition, 36-minute running on the treadmill was conducted in interval group through alternate sets including 1 minute with 90-95% of maximum consumed oxygen and 3 minutes with 50% of maximum consumed oxygen. Blood sampling was done following 12-hour night fasting at 3 stages including before, immediately after, and 60 minutes after the exercises. Data was analyzed by SPSS 20 software using repeated ANOVA, LSD post-hoc, and independent T tests.

Findings: Both severe exercises significantly increased homocysteine and HP72 levels (p<0.05), decreasing after 1-hour recovery compared to the interval immediately after the exercise. Nevertheless, HSP72 levels remained significantly higher than the basic levels (p<0.05). 

Conclusion: Both moderate-intensity continuous and high-intensity interval exercises similarly change homocysteine and HSP72 levels in the sedentary women.