Showing 4 results for Mansouri
Ar. Iraj Mansouri, Dr. E. Noruzian, Dr. A. Gholamhoseinian,
Volume 11, Issue 1 (vol- 1 2005)
Abstract
Background and Aim: Most of copper present in blood is incorporated in the structure of a protein called ceruloplasmin and only a small fraction of it is present as free copper. Undoubtedly, the separate determination of each of these forms needs a convenient, reliable, and accurate method of measurement. Therefore, an investigation on the precision and the accuracy of the method for determination of ceruloplasmin and the relationship between its concentration and the total copper level was studied
Materials and Methods: In the present study, 90 serum samples from which 43 accessions belonged to men and 47 accessions belonged to women were collected from the laboratory of Kerman General Hospital, and their ceruloplosmin and total copper level were determined. Total copper levels were measured by flame atomic absorption spectroscopy (AAS), while the concentration of ceruloplasmin was determined by enzymatic oxidation of p-phenylenediamine method.
Results: The results obtained indicate that the average levels of copper in the serum for men and women were 119±40µg/dl and 129±39µg/dl, and ceruloplasmin for them 36±11mg/dl and 37±11mg/dl, respectively. It should be mentioned that, the data, disregarding their sex, were found to be 124±38µg/dl and 36±11mg/dl respectively. The effect of temperature and storage on the level of ceruloplasmin was also studied. The results showed that keeping serum at room temperature for a long period does not significantly affect the ceruloplasmin level. The linear relationship between the concentration of ceruloplasmin and level of total copper was obtained as: Copper (µg/dl)=2.73+3.34 (mg/dl of ceruloplasmin).
Conclusion: It seems that one could easily determine the ceruloplasmin concentration and then by referring to the above relationship calculate the otherwise hard to measure concentration of copper present in the serum. Also long time storage of the serum does not affect the Enzyme activity.
Dr Shahla Khosrovan, Mohammad Reza Mansourian, Dr Mojtaba Kianmehr, Hedayatollah Shams, Leila Sadegh Moghaddam, Ali Delshad Noghabi,
Volume 16, Issue 4 (2-2011)
Abstract
Abstract
Background and Aims: Quality in educational system deserves special importance and its purpose is the maximum use of resources. Also, evaluation plays a fundamental role in quality improvement. Therefore, this study was designed to investigate the internal evaluation of community and mental health nursing department of Gonabad university of medical sciences.
Materials and Methods: This study was a descriptive one. The sample included faculty members, managers, students and related resources as well as the documents of community and mental health nursing department of Gonabad university of medical sciences. A non-random selection based on the objective was used for their selection. Data collection tools were a questionnaire and a checklist. Moreover, observation, inquiry and focus group discussion were used to collect data. The data were analyzed via descriptive statistics.
Results: Evaluation resulted in 8 factors, 41 criteria and 212 markers that were studied and indicated that the total score of facilities and educational equipments were the highest (92.18%). The minimum score was allocated to educational courses, academic and nonacademic curricula (55.55%).
Conclusion: The department should attempt to maintain and promote the items with desired status according to progress of science and technology, they also should try to improve the factors that did not get high score on internal evaluation, by careful planning. University administrators also should provide necessary resources and good conditions to improve the group and achieve the best conditions.
Anita Mansouri, Farid Zayeri, Ahmad Reza Baghestani, Zahra Ghorbanifar, Hosein Delavar Kasmaei, Ali Sheidaei,
Volume 21, Issue 2 (Summer 2015)
Abstract
Aims: Among all types of headache, migraine is the third most prevalent disorder and seventh common cause of disability. In Old Persian medical literature, Coriander fruit have been introduced as a treatment of headache. The aim of this study was exploring the effect of Coriander fruit on severity and duration of migraine attacks. Materials & Methods: This randomized triple-blind, placebo-controlled clinical trial was conducted in the neurology clinic of Shohadaye Tajrish hospital in Tehran. Based on sample size formula for longitudinal data, a total number of 66 patients were randomly assigned into intervention and control groups. Intervention group received common medicine plus Coriander fruit and the control group received common medicine plus placebo and both were followed during four weeks after intervention. For analyzing the data, random effect and transition models were utilized and the results were compared using Akaike criteria. Findings: The average of attacks duration in the intervention group was 4.27 hours less than the control group (p<0.001). Also, mean severity of migraine attacks in the intervention group was 2.81 (based on VAS scale) less than control group (p<0.001). Conclusion: Coriander fruit reduces the duration and severity of migraine attacks. Also, considering the duration and severity of last migraine attacks is necessary for prediction.
Fereshteh Asgharzadeh, Mahmoud Hosseini, Farimah Beheshti, Hassan Rakhshandeh, Somaieh Mansouri, Akbar Anaeigoudari,
Volume 27, Issue 4 (Autumn 2021)
Abstract
Aims: Oxidative stress plays an essential role in the pathogenesis of seizures. In this study, we investigated the effect of ethyl acetate fraction of Tanacetum parthenium against oxidative brain damage in a pentylenetetrazole(PTZ)-induced seizure model in mice.
Methods & Materials: In this experimental study, mice were divided into 6 groups: control, PTZ, and 4 other groups that, besides PTZ, received 25, 50, 100, and 200 mg/kg of the fraction. PTZ (100 mg/kg) and a fraction (30 min before PTZ) were administered intraperitoneally for 3 weeks. Delay in the onset of the minimal clonic seizure (MCS), generalized tonic-clonic seizure (GTCS), and the level of oxidative stress indexes in cortical and hippocampal tissues were measured.
Findings: Pretreatment with fraction resulted in postponing the onset seizures in the Fraction+PTZ groups compared to the PTZ group (P<0.05, P<0.01, and P<0.001). In addition, all doses of ethyl acetate fraction decreased the concentration of malondialdehyde (MDA) and increased the level of tom thiol groups and the activity of superoxide dismutase and catalase enzymes in the brain tissues compared to the PTZ group.
Conclusion: Ethyl acetate fraction of Tanacetum parthenium attenuated PTZ-stimulated seizures through improving brain tissue oxidative stress.
