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Showing 2 results for Blood [http:www.ncbi.nlm.nih.govmesh68001769]

Mojtaba Kianmehr, Ashraf Saber, Reza Ahmadi, Jalil Moshari, Mahdi Basiri Moghadam,
Volume 20, Issue 2 (7-2014)
Abstract

Abstract Aims: Diarrhea is one of the major causes of morbidity and mortality in children in developing countries after respiratory infections. The aim of this study was to investigate the effect of simultaneous consumption of rice soup and Oral Rehydration Salt on weight gain and blood factors in 8-24 months old children with acute diarrhea. Materials & Methods: This study is a controlled clinical trial which was done on 40 children 8 to 24 months old with acute diarrhea hospitalized in the pediatric ward in 22th Bahman hospital, Gonabad in 2013 who were selected using simple sampling method. Subjects were assigned into control and intervention groups using random allocation. The weight gain rate and blood factors including creatinine, urea, hemoglobin, hematocrit, bicarbonate and pH were studied and compared before and after intervention. Data was analyzed using SPSS 14.5 software using Chi-square, independent T and Mann-Whitney tests. Findings: There was no significant difference between two groups in terms of blood factors such as creatinine, urea, hematocrit, pH and bicarbonate before and after intervention. Also the reduction in hemoglobin was not significant between two groups, but the reduction in urea and creatinine in intervention group was more than control group. The mean of weight gain in the first and second 24hours had significant difference between two groups and it was higher in intervention group rather than control group. Conclusion: Rice soup consumption is caused more weight gain in treatment of children with acute diarrhea. The rice soup has no effect on blood factors except urea and creatinine in children with acute diarrhea as well.
Abbasnezhad A.a., Niyazmand S., Mahmoud Abadi M., Soukhtanloo M., Rezaee S.a., Seyed Mousavi S.m.,
Volume 20, Issue 4 (1-2015)
Abstract

  Aims: Diabetes mellitus is associated by increased blood glucose level resulting from lack of Insulin or Insulin resistance in peripheral tissues or both. The aim of this study was to investigate the effects of Nigella sativa L. seed hydroalcoholic extract on blood biochemical parameters in STZ-induced diabetic rats.

  Materials & Methods: This interventional study was done on 60 male Wistar rats. Animals were randomly divided into 6 groups (n=10) including control, diabetic (receiving saline), groups receiving 100, 200 and 400mg/kg doses of the extract and positive control (receiving 300mg/kg Metformin). Animals were treated for 6 weeks with gavage from start (zero), 24 and 45 days of the study. Glucose, cholesterol, triglycerides, HDL and LDL were measured after 12hours of fasting. Data were analyzed by SPSS 16 software and One-way ANOVA, Tukey and Paired-T tests.

  Findings: Blood sugar levels in diabetic rats receiving 200mg/kg dose of the extract was reduced more significantly than other treated groups (p<0.01). There was a significant difference in cholesterol and triglyceride at day 45 in all treated groups compared to diabetic group (p<0.001). No significant difference was observed in HDL in groups. A significant reduction in LDL was observed in diabetic group treated with Metformin and Nigella extract at day 45.

  Conclusion: Nigella sativa L. extract reduces glucose, cholesterol, triglyceride, and LDL levels in diabetic rats.

 



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