@ARTICLE{Zendehdel Kh, author = {Ghahhari, J. and Vaezi, GhH. and Shariatifar, N. and Zendehdel Kh, M. and }, title = {The study of hydroalcoholic extract of Ziziphora tenuior on visceral pain with writhing test in mice}, volume = {15}, number = {2}, abstract ={Background and Aim: Ziziphora tenuior is a traditional herbal medicine widely used as a mild sedative, spasmolytic and antibacterial agent. In this study the effect of hydroalcoholic extract of Ziziphora tenuior on visceral pain was investigated. Materials and Methods: This experimental study performed on 40 N-MRI male mice (28±3g). Animals were randomly grouped into control, positive control and receivers of Ziziphora tenuior extract. Control and positive control groups received normal saline and indomethacin (5mg/kg), respectively. Treatment groups were injected with 50, 75 and 100 mg/kg of hydroalcoholic extract of Ziziphora tenuior. All injections were performed intraperitonealy (ip). Animals were injected with acetic acid 0.6% (10ml/kg) for visceral pain induction, 30 minutes after of each intraperitoneal administration. Antinociceptive effects were recorded by counting the number of writhes during 30 minutes. The data were analyzed by SPSS statistical software and One-Way ANOVA test. The significant was shown with (p }, URL = {http://imtj.gmu.ac.ir/article-1-594-en.html}, eprint = {http://imtj.gmu.ac.ir/article-1-594-en.pdf}, journal = {Internal Medicine Today}, doi = {}, year = {2009} }