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Background and Aim: Cardiac autonomic neuropathy (CAN) is one of diabetes micro-vascular complications associated with increased cardiovascular mortality. CAN is more frequent in patients with other diabetes micro-vascular complications. In this research we evaluated the relation between CAN and other diabetes micro-vascular complications. Materials and Methods: This research includes 41diabetic patients (25 female and 16 male with mean age of 44.9 yr and 8.6 yr of history of diabetes) who had regular evaluation in Kashan Diabetes center. All of them assessed for diabetes micro-vascular complications and CAN. Results: There wasn’t any meaningful statistical relationship between CAN and diabetic sensory neuropathy, retinopathy and nephropathy. Sensory neuropathy was the most frequent diabetic micro-vascular complications associated with CAN (71%). There wasn’t any evidence of CAN in 31% of the patients with sensory neuropathy while CAN had founded without sensory neuropathy in 21% of these patients. Conclusion: There wasn’t strong statistical correlation between CAN and other diabetic microvascular complications. Diabetic patients should be evaluated for CAN because it can’t be rule out in the absence of other microvascular complications.

Keywords: Cardiac autonomic neuropathy (CAN); Microvascular complication of diabetes; Diabetes mellitus

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