Volume 11, Issue 4 (vol- 4 2006)                   Intern Med Today 2006, 11(4): 37-41 | Back to browse issues page

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1- , fashrafzadeh@yahoo.com
Abstract:   (12676 Views)
Background and Aim:To determine neurodevelopmental outcome of term neonatal seizures in the age of 3months.Patients and methods: 46 term neonates with clinical seizures were included during 1 year. Data collected through using history, observation and examination in the day of the admission and in 3 months of life. Then results were analyzed. Results: From 46 term neonates 43.5% were girls and 56.5% boys. In 23% of the cases, first seizures occurred in the first day of life and overall in 84% of patients, seizures started in the first week. 63% of neonates had one type of seizures the most common type was tonic.In 39% interictal EEGs were abnormal. The etiologies were hypoxic ischemic encephalopathy (HLE) in 30.4% infection 19.6%, hypoglycemia 13%, other metabolic disorders in 13%, intracranial hemmorhage in 11%, cerebal dysgenesis 4%, hyperekplexia and familial neonatal seizures each of them 2% and 4% unknown. 2/3 of neonates were available in 3 months of life. 50% of them had abnormal neurodevelopment assessment. All neonates with seizures due to HIE were in this group (P=0.00).Seizures type and EEG findings don’t have significant correlation with abnormal developmental outcomes (P =0.6). Conclusion:Seizures type and EEG findings don’t have significant correlation with neurologic outcome in neonatal seizures, at 3 months of life, but the causes of seizures are determinative.
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Type of Study: Original | Subject: Internal Medicine
Received: 2008/05/25 | Published: 2006/01/15

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