Volume 21, Issue 1 (Spring 2015)                   Intern Med Today 2015, 21(1): 59-66 | Back to browse issues page

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Hamzei A, Basiri Mogadam M, Esmaeili M, Delshad Noghabi A. Comparison of the Effect of Lidocaine Spray on Blade of Laryngoscope with Intravenous Lidocaine on the Cardiovascular Responses to Laryngoscopy and Endotracheal Intubation. Intern Med Today 2015; 21 (1) :59-66
URL: http://imtj.gmu.ac.ir/article-1-2130-en.html
1- Anesthesia & Operating Room Department, Paramedical Faculty, Gonabad University of Medical Sciences, Gonabad, Iran
2- Nursing Department, Nursing & Midwifery Faculty, Gonabad University of Medical Science, Gonabad, Iran
3- Student Research Committee” and “Nursing Department, Nursing & Midwifery Faculty”, Gonabad University of Medical Sciences, Gonabad, Iran , mahdi.esmaeili395@gmail.com
Abstract:   (5635 Views)

Aims: Endotracheal intubation is an invasive technique which is associated with severe cardiovascular complications. This study aimed to compare the effects of lidocaine 10% spray on the laryngoscope blade with intravenous lidocaine on cardiovascular responses to laryngoscopy and intubation in elective surgical patients. Materials & Methods: In this clinical trial that is performed in 2013, 90 candidates of elective surgery in Gonobad City, Iran hospitals were randomly divided to three groups control (no drugs were used), intravenous lidocaine (three minutes before laryngoscopy) and lidocaine 10% (just before laryngoscopy). Heart rate and systolic blood pressure, diastolic blood pressure and mean arterial blood pressure were recorded immediately before, immediately after, and 1, 3 and 5min after laryngoscopy. Data were analyzed using SPSS 20 by repeated ANOVA and Tukey post hoc tests. Findings: There were significant differences in systolic, diastolic and mean arterial blood pressure between control group and each intravenous lidocaine and lidocaine 10% groups after laryngoscopy (p<0.001). There was no significant difference in any of the three variables between intravenous and spray groups. No significant difference was found between the three groups in heart rate (p=0.16). Conclusion: Compared with intravenous lidocaine administration, lidocaine 10% spray on the laryngoscope blade lead to better stability in blood pressure after laryngoscopy, but has no effect on the heart rate.

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Type of Study: Original | Subject: Anesthesiology
Received: 2015/01/13 | Accepted: 2015/03/17 | Published: 2015/03/17

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