Volume 22, Issue 3 (summer 2016)                   Intern Med Today 2016, 22(3): 177-183 | Back to browse issues page

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Kazemi A, Rahmati M, Akhondi M. Effect of 6 Weeks of High-Intensity Interval Training with Cinnamon Supplementation on Serum Apelin Concentration and Insulin Resistance in Overweight Boys. Intern Med Today 2016; 22 (3) :177-183
URL: http://imtj.gmu.ac.ir/article-1-2281-en.html
1- Physical Education Department, Literature & Humanities Faculty, Vali-e-Asr University of Rafsanjan, Rafsanjan, Iran , rkazemi22@yahoo.com
2- Physical Education Department, Literature & Humanities Faculty, Lorestan University, Khoramabad, Iran
3- Physical Education Department, Literature & Humanities Faculty, Kerman University, Kerman,
Abstract:   (5317 Views)

Aims: Playing an important role in regulating glucose hemostasis, apelin might empower the correlation between any increase in the adipose tissue mass and obesity and the correlated metabolic diseases. The aim of this study was to investigate the effects of 6-week intensive periodic massive exercises with cinnamon supplementation on the apelin serum concentration and insulin resistance in the overweight boys.  

Materials & Methods: In the semi-experimental study, 40 male overweight students were studied in Zahedan in 2014. The samples, randomly selected, were divided into four groups including exercise, exercise and supplementation, supplementation, and control. 6-week intensive periodic massive exercises were done in the exercise groups. In addition, three 380mg-cinnamon capsules were administrated in the supplementation groups. Blood sampling was done from the subjects 48 hours before and after the exercise program. Apelin, glucose, and insulin levels were measured. Data was analyzed by SPSS 19 software using one-way and two-way ANOVA tests and covariance analysis.    

Findings: There were significant differences between “exercise” and “exercise and supplementation” groups and “control” group in apelin and insulin resistance levels after the exercise program (p=0.0001). In addition, there was a significant difference between “cinnamon supplementation” and “control” groups in insulin resistance (p=0.001).There were significant differences between the exercise groups and supplementation group in apelin (p=0.0001) and insulin resistance (p=0.003) levels.

Conclusion: The serum apelin level and the insulin resistance index in the overweight boys are reduced by 6-week intense periodic massive exercises. In addition, the cinnamon supplementation only reduces the insulin resistance index.

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Type of Study: Original | Subject: Laboratory Medicine
Received: 2015/08/6 | Accepted: 2016/05/11 | Published: 2016/05/24

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