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Background and Aim: Nowadays it is known that H.pylori, NSAIDs & acid are the most important factors in peptic ulcer formation. The rate of H.pylori infection, is increasing according to the increasing but in developing countries it’s more in children. This study was done to certify serologic assessment of Helicobacter pylori infection in Golestan medical students. Materials and Methods: In this descriptive cross-sectional study after providing a questionnaire having demographic information. Blood samples were send to a certain laboratory and IgG anti-H.pylori titers was measured with ELISA. Demographic questionnaires were completed. Data was analyzed with x2 test. Results: 16 cases were sero-positive (4.2%) and 340 cases were sero-negative (88.3%), others were equivocal. There were no meaningful relationship between seropositiveness and other variables, Although a meaningful relationship were observed between history of GI disorder in person and seropositivity in him/her. Conclusion: Sero-positivity of H.pylori in our University is in lower level (4.2% versus 10%), but more extreme screening studies are needed.

Keywords: H.pylori; IgG; ELISA; Student

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