Volume 23, Issue 4 (Autumn 2017)                   Intern Med Today 2017, 23(4): 273-277 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Habibian M, Valinejad A. Comparison of Brain-Derived Neurotrophic Factor (BDNF) and Insulin-like Growth Factor 1 (IGF-1) Responses to Different Endurance Training Intensities in Runner Men. Intern Med Today 2017; 23 (4) :273-277
URL: http://imtj.gmu.ac.ir/article-1-2597-en.html
1- Physical Education Department, Human Sciences Faculty, Qaemshahar Branch, Islamic Azad University, Qaemshahar, Iran , habibian_m@yahoo.com
2- Physical Education Department, Human Sciences Faculty, Sari Branch, Islamic Azad University, Sari, Iran
Abstract:   (3600 Views)
Aims: Blood neurotrophins, such as Brain-Derived Neurotrophic Factor (BDNF) and Insulin-like Growth Factor 1 (IGF-1), mediate exercise- induced health benefits in humans. The purpose of this study was to compare the response of BDNF and IGF-1 to different endurance training intensities in runner men.
Materials & Methods: In this semi-experimental study with pre-test-posttest design in 2015, 10 people of male runners from Gorgan were selected through purposeful and accessible sampling. The endurance training protocol was 6 km running with moderate (70-75% of heart rate reserve) or severe (80-85% of heart rate reserve) intensity, which was performed within a week's interval. Fasting blood samples were collected before and immediately after both acute training sessions and serum levels of BDNF and IGF-1 were measured by ELISA and radioimmunoassay enzyme. Data were analyzed by SPSS 20 software using independent t-test and paired t-test.
Findings: Both acute endurance training significantly increased serum levels of BDNF and IGF-1 in runners, but high intensity endurance exercises increased BDNF levels in comparison with moderate intensity (p<0.05), while no significant difference was observed between IGF-1 response to different intensities of endurance training (p>0.05).
Conclusion: Serum BDNF response in endurance athletes is affected by the intensity of exercise, so that the effect of high intensity endurance training on BDNF levels is greater than moderate intensity exercise, but the response of IGF-1 to acute endurance training is independent of the intensity of exercise.
Full-Text [PDF 499 kb]   (1628 Downloads)    
Type of Study: Original | Subject: Physiology
Received: 2016/09/21 | Accepted: 2017/07/4 | Published: 2017/09/26

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2023 CC BY-NC 4.0 | Internal Medicine Today

Designed & Developed by : Yektaweb