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Background and Aim: Acute myocardial infarction is one of the main causes of mortality and morbidity in developed and under developed countries. The aim of the present study was to evaluate the changes in mortality and risk factors in patients with acute myocardial infarction in Birjand from 1994-2003. Materials and Methods: This descriptive analytical study was based on patients that admitted due to acute myocardial infarction in Birjand hospital from 1994 -2003. The source of data collection were questionnaires that completed by two educated nurses with supervision by cardiologist. Then data entered to SPSS and analyzed by t-test and Chi-Square at =0.05. Results: From 918 patients that hospitalized for acute myocardial infarction during 1994-2003, 84 patients was died (9.1%). Changes in mortality during this ten years was showed reduction of mortality (14.7% in 1994- 6% in 2003). In this study, 319 patients (34.7%) had no risk factor and others had at least one risk factors. Prevalence of risk factors was increased for all risk factors, but prevalence of hyperlipidemia (18.2%, 30.1% P<0.001) and smoking (18.2%, 23.5% P=0.03) increased statistically significantly during ten years. Conclusion: Because of increasing in prevalence of cardiovascular risk factor in these 10 years, is needed to design interventional program for reducing this risk factors.

Keywords: Mortality; Risk factor; Acute myocardial infection; Birjand

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