Volume 30, Issue 1 (Winter 2023)
Intern Med Today 2023, 30(1): 0-0 |
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Eshghizadeh M, irani H, Ebrahimi N, Ilkhani M, Rajaee M. Treatment Adherence in Children with Cancer: A Mixed-Method Narrative Review. Intern Med Today 2023; 30 (1)
URL: http://imtj.gmu.ac.ir/article-1-4092-en.html
URL: http://imtj.gmu.ac.ir/article-1-4092-en.html
1- PhD Student in Nursing, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2- MSc in Nursing, Department of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran
3- Department of Medical Surgical Nursing, School of Nursing, Gonabad University of Medical Sciences,Gonabad, Iran
4- PhD in Nursing, Associate Professor, Faculty of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
5- Master Student of Nursing, Student Research committee, Gonabad University of Medical Sciences, Gonabad, Iran ,mobinarajaee2020@gmail.com
2- MSc in Nursing, Department of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran
3- Department of Medical Surgical Nursing, School of Nursing, Gonabad University of Medical Sciences,Gonabad, Iran
4- PhD in Nursing, Associate Professor, Faculty of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
5- Master Student of Nursing, Student Research committee, Gonabad University of Medical Sciences, Gonabad, Iran ,
Abstract: (14 Views)
Aims Non-adherence to treatment is a significant barrier to the management of childhood diseases, including cancer. Cancer survivors experience a high mortality rate due to secondary complications. This study aimed to explore the level of adherence to treatment in children with cancer.
Materials & Methods In a mixed-method narrative review, three databases — PubMed, Scopus, and the Cochrane Library — were searched in 2021-22. A total of 227 articles were retrieved. After initial examination, 43 articles were retained, of which 28 were excluded (5 due to duplication and 23 for reasons, such as participants’ age, type of disease, and unavailability of full text, and 6 for poor quality). Finally, nine articles were included in the study. The inclusion criteria included English language, no time limit, type of cancer, research and review articles, qualitative studies, and the target age of childhood.
Findings Among the remaining nine articles, six were descriptive in type, two were clinical trials, and one was a review. Given a wide range of article designs, a mixed-methods approach was employed, along with a theme analysis (for studies with similar designs). The extracted themes were summarized under four main topics: prevalence of treatment adherence in children, factors related to adherence, adherence measurement instruments, and interventions to promote treatment adherence.
Conclusion Treatment adherence in children does not reach the ideal level of 95%, but interventions can improve treatment adherence. Treatment adherence is a multifactorial construct that is significantly influenced by children's families. This review has implications for health policy makers regarding pediatric cancer.
Materials & Methods In a mixed-method narrative review, three databases — PubMed, Scopus, and the Cochrane Library — were searched in 2021-22. A total of 227 articles were retrieved. After initial examination, 43 articles were retained, of which 28 were excluded (5 due to duplication and 23 for reasons, such as participants’ age, type of disease, and unavailability of full text, and 6 for poor quality). Finally, nine articles were included in the study. The inclusion criteria included English language, no time limit, type of cancer, research and review articles, qualitative studies, and the target age of childhood.
Findings Among the remaining nine articles, six were descriptive in type, two were clinical trials, and one was a review. Given a wide range of article designs, a mixed-methods approach was employed, along with a theme analysis (for studies with similar designs). The extracted themes were summarized under four main topics: prevalence of treatment adherence in children, factors related to adherence, adherence measurement instruments, and interventions to promote treatment adherence.
Conclusion Treatment adherence in children does not reach the ideal level of 95%, but interventions can improve treatment adherence. Treatment adherence is a multifactorial construct that is significantly influenced by children's families. This review has implications for health policy makers regarding pediatric cancer.
Type of Study: Review |
Subject:
Pediatrics
Received: 2025/06/30 | Accepted: 2025/10/12 | Published: 2023/12/7
Received: 2025/06/30 | Accepted: 2025/10/12 | Published: 2023/12/7
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