Volume 18, Issue 2 (7-2012)                   Intern Med Today 2012, 18(2): 27-36 | Back to browse issues page

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Dabidi Roshan V, Hemmati Safarshahi Y, Nooredinini H G. Interactive Effect of the 8-week Endurance Exercise and Turmeric Extract on the Regional Bone Mineral Density of Femur bone. Intern Med Today 2012; 18 (2) :27-36
URL: http://imtj.gmu.ac.ir/article-1-891-en.html
1- , vdabidiroshan@yahoo.com
Abstract:   (8609 Views)
Background and Aim: Some studies have shown the detrimental effect of lead on bone mineral density. We investigated the interactive effects of exercise and turmeric extract on the regional bone mineral density of femur bone in rats exposed to lead acetate. Materials and Methods: In an experimental study, 50 rats were randomly assigned to groups Lead acetate, Exercise+lead, Turmeric Supplementation+lead , Exercise+Turmeric+Lead and control (Sham-operate) group. Rats received lead acetate (20 mg/kg) and/or turmeric extract (30 mg/kg), 3 days in a week for 8 weeks. Endurance exercise was performed 5 days a week, with progressive speed and time. The data of BMD and the other variables were analyzed by using SPSS software version 16 employing one-way ANOVA at P≤ 0.05 level. Results: MDA and TAC concentrations were significantly lower and higher in the exercise, turmeric and the exercise+turmeric groups, compared with lead group, respectively. In addition, endurance exercise and/or training+turmeric not only led to decrease in lead-induced BMD levels, but also resulted in a significant increase in BMD levels, in particular, femur and distal epiphysis regions compared with lead and sham groups. Conclusion: The lifestyle such as exercise training and antioxidant supplementation can offer beneficial effects for preventing loss Lead-induced administration in femur BMD, in particular, in regions with spongy bony tissue.
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Type of Study: Original | Subject: Basic Medical Science
Received: 2010/10/9 | Accepted: 2012/07/8 | Published: 2012/07/15

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