Volume 16, Issue 3 (Autumn 2010)                   Intern Med Today 2010, 16(3): 71-76 | Back to browse issues page

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Shahraki M R, Mirshekari H, Harati M, Shahraki A R. Evaluation of Tamarindus Indicia Seed Aqueous Extract on Tail Flick Reaction Time and Serum DHEA in Fructose-fed Male Rats. Intern Med Today 2010; 16 (3) :71-76
URL: http://imtj.gmu.ac.ir/article-1-967-en.html
1- , m_shahrakim@yahoo.com
Abstract:   (12260 Views)
Background and Aim: Metabolic syndrome is a metabolic disorder that affects on the Diabetes mellitus pathophysiology and alters the cell excitability and serum DHEAS value. The aim of this study was to evaluate the effect of Tamarindus indicia seed aqueous extract on tail flick reaction time and DHEAS value in fructose-fed male rats. Materials and Methods: This experiment was performed on 30 male rats which were divided into three equal groups of sham control(C), Fructose-fed (F) and fructose-fed receiving Tamarindus indicia seed aqueous extract (FT). At the end of the study, tail flick reaction time and serum DHEAS were measured. The obtained data were analyzed by SPSS software version.11. The results were expressed as mean ±SD and statistical differences were considered significant (P<0.05). Results: The results showed that tail flick reaction time in FT group significantly decreased compared with that of F group however, serum DHEAS value in this group significantly increased compared with that of F group. Conclusion: The results indicated that Tamarindus indicia seed aqueous extract can increase the cell excitability and serum DHEAS in fructose-fed male rats. Future studies will probably show the exact mechanism.
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Type of Study: Original | Subject: Basic Medical Science
Received: 2010/12/11 | Accepted: 2021/12/27 | Published: 2010/12/15

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