Volume 24, Issue 1 (Winter 2018)
Intern Med Today 2018, 24(1): 23-28 |
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Godarzi N, Hamzei A, Basiri Moghadam M, Ghenaati J, Torkamani Noghabi M, Zarif Najafi P et al . Comparing Effect of Safranal and Diazepam in Reducing Preoperative Anxiety and Improving Vital Symptoms. Intern Med Today 2018; 24 (1) :23-28
URL: http://imtj.gmu.ac.ir/article-1-2804-en.html
URL: http://imtj.gmu.ac.ir/article-1-2804-en.html
N. Godarzi1 
, A. Hamzei2 , M. Basiri Moghadam3 , J. Ghenaati4 , M. Torkamani Noghabi4 , P. Zarif Najafi5 , S. Pasban-Noghabi * 6
, A. Hamzei2 , M. Basiri Moghadam3 , J. Ghenaati4 , M. Torkamani Noghabi4 , P. Zarif Najafi5 , S. Pasban-Noghabi * 6
1- Basic Sciences Department, Medicine Faculty, AJA University of Medical Sciences, Tehran, Iran
2- Operating & Anesthesia Department, Paramedicine Faculty, Gonabad University of Medical Sciences, Gonabad, Iran
3- “Social Development & Health Promotion Research Center” and “Pediatric Nursing Department, Nursing & Midwifery Faculty”, Gonabad University of Medical Sciences, Gonabad, Iran
4- Basic Sciences Department, Medicine Faculty, Gonabad University of Medical Sciences, Gonabad, Iran
5- Obstetric & Gynecology Department, Medicine Faculty, Medical Sciences Branch, Islamic Azad University Mashhad, Mashhad, Iran
6- Student Research Committee, Nursing Department, Nursing & Midwifery Faculty, Gonabad University of Medical Sciences, Gonabad, Iran , pasban_saeid@yahoo.com
2- Operating & Anesthesia Department, Paramedicine Faculty, Gonabad University of Medical Sciences, Gonabad, Iran
3- “Social Development & Health Promotion Research Center” and “Pediatric Nursing Department, Nursing & Midwifery Faculty”, Gonabad University of Medical Sciences, Gonabad, Iran
4- Basic Sciences Department, Medicine Faculty, Gonabad University of Medical Sciences, Gonabad, Iran
5- Obstetric & Gynecology Department, Medicine Faculty, Medical Sciences Branch, Islamic Azad University Mashhad, Mashhad, Iran
6- Student Research Committee, Nursing Department, Nursing & Midwifery Faculty, Gonabad University of Medical Sciences, Gonabad, Iran , pasban_saeid@yahoo.com
Abstract: (6385 Views)
Aim: Preoperative anxiety is an unpleasant manner created by fear of surgery. The aim of the present study was to compare the effects of diazepam pill with Safranal in reducing preoperative anxiety and improving vital symptoms.
Material and Methods: In this double blind randomized clinical trial, 54 patients who were candidates of urology surgery (varicocele) in 15th Khordad Hospital, Gonabad, Iran, were selected by purposive sampling method, using a randomized numbers table; they were divided into intervention (n=29) and control group (n=25). The patients in intervention group received 15mg Safranal and the patients in control group received 5mg oral diazepam 3 hours before surgery. The State-Trait Anxiety Inventory (STAI) questionnaire was completed by the patients prior to the intervention and just at the entrance to the surgery room, and the vital symptoms of the patient were evaluated. The data were analyzed by SPSS 11.5 software, using of Chi-square and independent sample t-test.
Findings: After intervention, the trait anxiety in the Safranal group was significantly lower than diazepam group (p=0.007) and before the intervention (p=0.002). Also, diastolic blood pressure decreased significantly in the Safranal group compared with the diazepam group (p=0.049).
Conclusion: Saffranal consumption before surgery is more effective than diazepam consumption in reducing the trait anxiety, but it does not affect state anxiety. Also, compared to diazepam, Saffranal consumption leads to a more reduction in diastolic blood pressure, while it does not affect systolic blood pressure and heart rate.
Material and Methods: In this double blind randomized clinical trial, 54 patients who were candidates of urology surgery (varicocele) in 15th Khordad Hospital, Gonabad, Iran, were selected by purposive sampling method, using a randomized numbers table; they were divided into intervention (n=29) and control group (n=25). The patients in intervention group received 15mg Safranal and the patients in control group received 5mg oral diazepam 3 hours before surgery. The State-Trait Anxiety Inventory (STAI) questionnaire was completed by the patients prior to the intervention and just at the entrance to the surgery room, and the vital symptoms of the patient were evaluated. The data were analyzed by SPSS 11.5 software, using of Chi-square and independent sample t-test.
Findings: After intervention, the trait anxiety in the Safranal group was significantly lower than diazepam group (p=0.007) and before the intervention (p=0.002). Also, diastolic blood pressure decreased significantly in the Safranal group compared with the diazepam group (p=0.049).
Conclusion: Saffranal consumption before surgery is more effective than diazepam consumption in reducing the trait anxiety, but it does not affect state anxiety. Also, compared to diazepam, Saffranal consumption leads to a more reduction in diastolic blood pressure, while it does not affect systolic blood pressure and heart rate.
Keywords: Safranal [https://www.ncbi.nlm.nih.gov/mesh/67087963], Diazepam [https://www.ncbi.nlm.nih.gov/mesh/68003975], Preoperative Period [https://www.ncbi.nlm.nih.gov/mesh/68057234], Anxiety [https://www.ncbi.nlm.nih.gov/mesh/68001007]
Type of Study: Original |
Subject:
Anesthesiology
Received: 2017/06/30 | Accepted: 2017/12/5 | Published: 2018/01/1
Received: 2017/06/30 | Accepted: 2017/12/5 | Published: 2018/01/1
English Expanded Abstract [HTML 25 KB] (109 Download)
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