Aims: Cardio-vascular diseases are of the most important health and treatment problems in the recent industrialized societies. The conducted studies show that noise and vibrations, as types of pollution, are risk factors for the cardio-vascular diseases. The aim of this study was to investigate the effects of short-term and long-term facing with noise pollution on some heart biochemical and electrophysiological parameters in the rats. 

Materials & Methods: In the experimental study, 60 male Wistar rats were randomly divided into two experimental groups including short-term (one-day facing) and long-term (30-day facing). And each one included one control group and three experimental groups (4-, 8-, and 12-hour noise facing). At last, different electrophysiological parameters of heart function were investigated via recorded electrocardiograms. The levels of creatine phosphokinase and troponin I enzymes were measured, to investigate myocardial injury. Data was analyzed by SPSS 21 software using One-way ANOVA and Tukey’s post-hoc tests.   

Findings: Short-term (4-hour) facing with noise pollution only led to a reduction in PR interval (p<0.05). Long term (8- and 12-hour) facing with noise pollution considerably reduced PR, QT, and QTc wave intervals, while increased QRS complex voltage (p<0.05). Short-tem (4-hour) and long-term (8 to 12-hour) facing led to an increase in the heart rate (p<0.05). There was no significant difference in the serum level of creatine phosphokinase and troponin I enzymes between different groups. 

Conclusion: Through changes in the hemodynamic factors, continuous facing with noise pollution can increase heart rate and function in the rats.