Volume 12, Issue 1 (vol-1 2006)                   Intern Med Today 2006, 12(1): 5-10 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Tayebi-Meybodi N, Amooeian S, Farzadnia M, Memar B, Mahmoudi M, Mozouni M et al . Clinical and laboratory evaluation in 17 cases of macroprolactinemia identified by polyethylene glycol precipitation test. Intern Med Today 2006; 12 (1) :5-10
URL: http://imtj.gmu.ac.ir/article-1-50-en.html
1- , mhdfarzadnia@yahoo.com
Abstract:   (13671 Views)
Abstract Background and Aim: Macroprolactinemia in which most circulating PRL forms Big Big PRL (>150KD), is a major causes of Idiopathic Hyperprolactinemia with mild or lack of symptoms. We aimed in this study to introduce a simple and inexpensive polyethylene Glycol precipitation test (PEG)for macroprolactin evaluation and avoiding other expensive diagnostic investigations also evaluation of classic hyperprolactinemia symptoms in macroprolactinemic patients Materials and Methods: In this descriptive study, serum prolactin was measured before and after precipitation of macroprolactin by polyethylene glycole in 90 patients with hyperprolactinemia (PRL>30µg/L), furthermore clinical and radiographic findings recorded. Results: 18.8% of cases were macroprolactinemic without hyperprolactinemic classic symptom. Conclusion: Regarding to high prevalence of macroprolactinemia and lack of classic symptoms of hyperprolactinemia and to avoid diagnostic and trapeutic pitfalls the screening for macroprolactin in all hyperprolactinmia recommended.
Full-Text [DOC 103 kb]   (12226 Downloads)    
Type of Study: Original | Subject: Internal Medicine
Received: 2007/07/3 | Published: 2006/04/15

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2023 CC BY-NC 4.0 | Internal Medicine Today

Designed & Developed by : Yektaweb